PND37 PATIENT AND PHYSICIAN GLOBAL PERCEPTION OF LEVODOPA/ CARBIDOPA/ENTACAPONE VS. LEVODOPA/CARBIDOPA IN PATIENTS WITH PARKINSON'S DISEASE EXPERIENCING EARLY WEARING-OFF
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چکیده
منابع مشابه
Factors Predictive of the Development of Levodopa-Induced Dyskinesia and Wearing-Off in Parkinson's Disease
I read the interesting report by Olanow et al. regarding factors predictive of the development of levodopa (L-dopa)-induced dyskinesia and wearing-off in Parkinson’s disease. L-Dopa has been widely used for more than 40 years, but a dose-finding study was never performed. I congratulate the authors for addressing this very important issue of L-dopa dosing. Their study provides scientific ration...
متن کاملAsian perspectives on the recognition and management of levodopa 'wearing-off' in Parkinson's disease.
Most Parkinson's disease patients will receive levodopa therapy, and of these, the majority will develop some levodopa-induced complications. For many patients, the first complication to develop is the decline in the duration of therapeutic benefit of each levodopa dose, a phenomenon commonly termed 'wearing-off'. There is already extensive literature documenting the epidemiology and management...
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15 صفحه اولSemantic activation in Parkinson's disease patients on and off levodopa.
Research suggests that dopamine may exert a neuromodulatory influence on automatic spreading activation within semantic networks. In order to investigate the influence of dopamine depletion on semantic activation in Parkinson's disease (PD), nine patients with PD performed a lexical decision task when on and off levodopa medication. Eleven healthy controls matched to the PD patients in terms of...
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ژورنال
عنوان ژورنال: Value in Health
سال: 2010
ISSN: 1098-3015
DOI: 10.1016/s1098-3015(11)72618-3